Research Support Office, Okayama University of Science 
Faculty of Life Science, Department of Medical Technology
- Associate professor
- Nozomu MATSUNAGA
- Research Field
pathogenic microorganisms,
- Keyword(s)
Host-pathogen interaction, adhesion molecule, wound healing
- Research theme
-
- The effects of <ｉ>Clostridium perfringens Fibronectin-binding proteins (Fbps)
- The interaction of dermatopontin with Fbps
- Role of peptidoglycan hydrolase in Fbps
- The affects of Fbps on wound healing
Outline of research activities
Infectious diseases caused by bacteria begin with the attachment (Binding) of bacteria to the host. We use <ｉ>Clostridium perfringens</ｉ>, one of the pathogenic bacteria, as wound infection model. We are studying host-pathogen interaction from the following viewpoints.
1. Interaction between fibronectin and fibronectin binding protein (Fbps) of <ｉ>C. perfringens</ｉ>
2. The effect of Fbps on dermatopontin (DPT)-induced fibronectin fibrosis.
3. Fbps functions as a peptidoglycan hydrolyzing enzyme
4. The effect of Fbps on wound healing
- Desired cooperation
-
- The development of novel antibiotics by applying <ｉ>C. perfringens Fbps
- Application of <ｉ>C. perfringens Fbps to dermatopontin-induced tissue injury