Research Support Office, Okayama University of Science 
Faculty of Engineering, Department of Applied Chemistry
- Lecturer
- Yasuhiro OKUDA
- Research Field
Organic Synthesis, Organometallic Chemistry, Theoretical Calculation
- Keyword(s)
Organic Synthesis, Reaction Design, Catalytic Transformation, Organic Material, Pharmaceutics
- Research theme
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- Development of New Reactions Accelerated by Transition-Metal Catalysts
- Synthesis of Bioactive Compounds
- Design and Synthesis of Organic Materials
Outline of research activities
Our laboratory focused on a phosphoryl (Ph2P(O)) group’s chemistry as an electron-withdrawing and removable protecting group on terminal alkynes, development of new reation and synthesis of functional molecules are currently investigated. For example, we demonstrated a process-controlled regiodivergent synthesis of triazole derivatives with bromo(phosphoryl)ethyne as common starting material, an alternative synthesis of commercially available pharmaceutical molecule was also succeeded (Org. Lett. 2020, 22, 5099–5103.)
More recently, we synthesized novel π-extended aromatic amines from ynamine (= alkynylamine), and further applications to luminescence, photovoltaics and hole-transporting materials are in progress.
- Desired cooperation
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- Organic sythesis, drug discovery and material design employing ynamine (= alkynylamine) as a common starting material