Faculty of Life Science, Department of Bioscience
- Professor
- Koji MATSUURA
- Research Field
Physiology, Microfluidics,Assisted Reproductive Technology (ART)
- Keyword(s)
Sperm selection, Early embryo cluture, Mechanobiology
- Research theme
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- Paper-based devices for sperm motility analysis (See below)
- Development of dynamic embryo culture systems
- Energy metabolism in mammalian sperms
- Microfluidic cell separation
Outline of research activities
We have demonstrated an inexpensive and easy-to-handle device for monitoring mammalian sperm motility made by patterning a piece of paper and measuring the activity of a specific enzyme. After applying semen to the hydrophilic center circle of the patterned paper, a tetrazolium-based colorimetric assay data can be used to help estimate the percentage of motile human sperm (sperm motility) in semen based on the character that motile human sperm moved in and on the paper.
(Matsuura et al. 2014, 2017, 2019)

- Desired cooperation
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- Clinical application of developed microfluidic devices for ART Mulicenter clinical studies
- Microfluidic device application for cell handling