We are interested in the effects of the artificial environment of imaging systems on humans. We have studied both pros and cons effects. Examples of the good effects are viewers’ sense of power, immersion, and presence, in which the viewers feel as if they are in the space projected by the imaging system. The problem of quantifying these senses is that it is not possible to measure them with a measuring instrument. These characteristics related to human senses and sensitivity can quantified through subjective evaluations and questionnaires. At the same time, biometric measurements are performed to search for measurement items that may serve as biological indices. We are investigating the relationship between subjective evaluations and biological indices.
Conversely, undesirable effects are that a person watching 3D images or a shaky image may experience eye fatigue or a motion sickness. To clarify what can be done to minimize these undesirable effects, we are studying the relationship between the undesirable effects and presented images by subjective evaluations and biometric measurements. In this process, we measure eye movements, autonomic nervous system, and brain activity to quantify the degree of the undesirable effects. Based on these results, we have proposed measures to prevent and mitigate undesirable biological effects.

By taking advantage of pneumatic actuators that have features of higher force / mass ratio, lightweight and flexibility based on compressibility, we have developed low-cost wearable actuators and low-cost home-based rehabilitation devices that can be disposable after using it. Specifically, we developed a flexible pneumatic cylinder that can be used even if the cylinder bends. A spherical actuator that consists of two flexible pneumatic cylinders have been also developed as an application for portable rehabilitation device. We have also developed a low-cost wearable servo valve using buckled tubes, an artificial muscle with built-in displacement sensor and a pipe inspection robot using extension type flexible pneumatic actuators. In addition, aiming at globalization for students, all graduate students in our laboratory have presentation in international conferences.

We are developing the simple and effective methods for screening oxidative stress-induced environmental substances, and the functional foods to control the toxicity of environmental substances. Furthermore, in order to understand the psychological and physiological effects of the forest environment on humans, we are conducting comparative studies using biological oxidative and antioxidant biomarkers as indicators.

・Peptide-based drug design and synthesis:
Design and synthesis of bioactive small molecules from peptide hormons and proteins based on structure activity relationships.

・Chemical Biology Research:
Development of a method for discovery of novel drug target protein using small bioactive compounds as the probes.

I study the biosynthetic pathway of indican (a precursor of indigo). As an application, I attempt the mass production of indigo in E. coli.

I analyze the intracellular function of several unique proteins from a slime mold.

“Home economics” in school education aims to improve the skill of homemaking through the velationships between oneself and their family, their consumption habit, their eating habit, their dwelling life, their clothing life and so on.
“Home economics” is concerned with not only our claily life but some subjects life social studies and science. Moreover it’s very important to reflect on your home life so far.
I investigate how “Home economics” should be and I design exciting, satisfactory and practical classes.

CRM was developed by the laboratory of Yamaguchi is integrated in one database each company on another system decentralized information systems. Here, provides accurate customer information gathering, analysis and sharing. In addition, employees are working, you can take advantage of the system are. Plays the role of generating added value as a result, information infrastructure.

From this company is important, rather than in a specific department or human resources to implement CRM, employees share information, leverage and produce value added customer in problem-solving, while proposals to. It is a new concept of companies that cannot deliver value, judging by the value proposed by the companies using customer.

I am working for epidemiological research on infectious diseases in animals, especially dirofilariasis and ectoparasite infections in dogs and cats, to aim at contribution to prevention. Furthermore, I am working for development of new drugs for animals. And I am also expanding the appropriate use of drugs in animals through pharmacoepidemiological research on usage survey, re-examination of efficacy and incidence of side effects of already-existing drugs.
Photos are a cat flea and a tick. Cat fleas are mundanely detected on dogs as well as cats, and also on humans in recent years in Japan. Ticks have gotten a lot of attention recently as vectors of severe fever with thrombocytopenia syndrome (SFTS). I am working for development of ectoparasiticides.

Reproductive disorders in cows are major health and financial problems on farm. Endometritis and ovarian dysfunction such as cystic ovarian disease, ovarian quiescence, and ovulation failure often occur concurrently in cows. We have demonstrated that lipopolysaccharides (LPS) produced by Gram-negative bacteria suppress the function of granulosa cells in follicles, leading to ovarian dysfunction in cows.
It is our firm belief that further investigation for this mechanism are needed to enhance reproductive performance and support veterinarians on farm.

I aim to understand and evaluate the physical and mental conditions of livestock animals from the viewpoints of physiology and behavior, and to construct a rearing environment in which livestock animals can maximize their potential. In particular, we are conducting research on the effects of temperature on livestock animals and examining ways to supply healthy, safe, and high-quality livestock products to people even under climate change caused by global warming.

Typical gallbladder diseases in dogs include biliary sludge, gallbladder mucocele, and cholelithiasis, but the pathophysiology remains unclear. I am investigating safer treatment methods by clarifying the detailed pathophysiology of canine gallbladder disease.
In addition, the progress of diagnostic imaging technology in veterinary medicine is remarkable, and I am also working on the application of these data to surgical anatomy (vascular anatomy, etc.), and using these, considering a more safer surgical methods.

I am working for research on the causes, diagnosis and treatment of dermatosis and ear diseases in companion animals (dogs, cats and exotic pet animals). Furthermore, I am focusing on research on the treatment of infestation by fleas, ticks and Demodex mites. With regard to preventive veterinary medicine, the survey on the prevalence of infectious diseases in dogs and cats and further pharmacoepidemiological studies on vaccines, prophylactics for dirofilariasis, and ectoparasiticides for dogs and cats.

I am researching standards for exercising state jurisdiction in Internet. I am also researching ways to protect students from natural disasters. In addition, I am conducting a legal analysis of informed consent in veterinary medicine.

Teaching learning strategies that allow students to learn inquiringly in cooperation with their peers are attracting attention, as a learning activity that fosters 21st century academic ability, such as comprehensive inquiry time and inquiry activities for each subject that are included in the Course of Study and implemented at each school. In addition, the GIGA School Concept requires the use of ICT in such learning activities.
I am conducting research on effective teaching and learning strategies based on practical examples of inquiry-based learning, which is an educational activity required in such an era. In particular, practical training is emphasized in the Department of Informatics, and the development of learning materials and the accumulation of teaching plans are awaited so that students can acquire “information theory”, “information ethics”, “programming thinking ability”, and “practical ability to utilize information” by learning independently using ICT. Takahashi Laboratory has developed such teaching materials, analyzed practical cases, and conducted research on methods to measure the qualities and abilities of students, which is the basis for verifying their effectiveness.

We are conducting research using coordination chemistry techniques to create novel substances with unprecedented functionalities based on metal complexes. A metal complex is a compound in which a metal ion (such as copper or iron) forms strong bonds with surrounding molecules, known as ligands.
In metal complexes, the metal ion and ligands bind together in specific arrangements or shapes, forming a stable structure as a unified compound. Through these interactions, metal complexes can exhibit new functional properties that were not observed in the individual metal ions.
Recently, we have been synthesizing porphyrin derivatives containing metal ions at their centers and using these complexes as catalysts to explore oxidation reactions using only oxygen molecules from the air and light.

While using mechanical engineering (fluid dynamics, thermal engineering), applied physics (magneto science), and econometrics, I am conducting research on material informatics that integrates engineering and informatics. Practically, I analyze medical data using the methods of data mining and multivariate analysis. In the field of magneto science, I progress a technology called a “magnetic force booster” and succeeded in realizing a completely containerless protein crystal growth (see the photos). By the use of a magnetic levitation technique, I have also established in measuring the thermal properties of protein crystals.

We aim to contribute to the development of the wine industries and education, through our research.
Research and invstigation into wine, Japanese sake, fruits and functional foods. Invesigation of volatile compaounds in wine and its produvtion mechanisms. Especially, advanced analysis and evaluation of wine.Wine has favorable and characteristic flavor. We indentify the characteristic compounds in wine and investigate their production mechanisms.
Wine have multiple health functionalities since it is a fermented material. We investigate the health functionality of wine and fermented foods in vitro.And, we investigate the health functinalities of functinal components fermented foods.

Most of the reserch on grape is about table grapes in Japan. Because wine grapes are not cultivated so much before. However, recently many wine grapes have been cultivated, and high quality wines are produced in several wineries in Japan. Until now engineers in wine makers have studies in the wine developped countries such as France and brought back the wine making techniques to Japan. But, Japanese climate and soil type are quite different from those of foreign countries. Then it is required to the Japanese original techniques in viticulture and enology. It is the most important thing in wine making that wine grapes are cultivated by the suitable conditions in Japan. Our institute of viticulture and enology aims to be a base for technology and information for engineers in wineries of the surrounding ares.