We are developing the simple and effective methods for screening oxidative stress-induced environmental substances, and the functional foods to control the toxicity of environmental substances. Furthermore, in order to understand the psychological and physiological effects of the forest environment on humans, we are conducting comparative studies using biological oxidative and antioxidant biomarkers as indicators.

・Peptide-based drug design and synthesis:
Design and synthesis of bioactive small molecules from peptide hormons and proteins based on structure activity relationships.

・Chemical Biology Research:
Development of a method for discovery of novel drug target protein using small bioactive compounds as the probes.

I study the biosynthetic pathway of indican (a precursor of indigo). As an application, I attempt the mass production of indigo in E. coli.

I analyze the intracellular function of several unique proteins from a slime mold.

“Home economics” in school education aims to improve the skill of homemaking through the velationships between oneself and their family, their consumption habit, their eating habit, their dwelling life, their clothing life and so on.
“Home economics” is concerned with not only our claily life but some subjects life social studies and science. Moreover it’s very important to reflect on your home life so far.
I investigate how “Home economics” should be and I design exciting, satisfactory and practical classes.

Specializes in education through teaching materials, methods, curriculum design, teachers’ training for inter-linguistic and intercultural communication based on social psychology. In 2007, started “Primary School Project” in Democratic Republic of Congo through intercultural collaboration, has continuously introduced how to create an atmosphere for “mutual collaboration” and “sustainable relationship” with the local community, and is always working with young researchers on the fieldwork-based approach in exploring how to interpret social and cultural phenomena in local communities to develop a model school for the area. We have other related projects in Kagoshima, Yamaguchi, Nagano, Kanagawa, Akita, Aomori.

As my specialty is interlinguistic and intercultural communication based on education, and I am researching its curriculum design and teaching methods. Generally, when we think about intercultural communication, it is exchange with foreign countries that comes to mind. However, even when we are talking with Japanese people, a word can often be interpreted completely differently by the other person, due to individual understandings of the image evoked by that particular word that arises from our diverse backgrounds. Nevertheless, there is the mistaken impression that sharing a language or an interpretation equals understanding, and major communication gaps can arise before we know it.
What is more, my special field of research is the creation of environments for interlinguistic and intercultural communication that generate these kinds of “discoveries.” What steps are required, what kind of settings do we need to create, and what kind of program do we need to assemble? This involves developing a curriculum design, creating an environment that generates sustainable shared understandings as quickly and naturally as possible, and coming up with the methodology to teach the required content and language, for example. We are undertaking this research by putting these concepts into practice through specific projects.

“Was that policy or promotion effective?” I answer this using data and theory — applying consumer behavior models (e.g., Theory of Planned Behavior) to longitudinal survey data before and after implementation to verify causality, not just correlation. I quantify how attitude change translates into actual behavior (purchases, participation, subscriptions, etc.) to pinpoint what drove results. Whether you’re a local government navigating KPI/KGI design or a company evaluating promotions, we bring proven experience across dining-out demand, disaster prevention, and food loss reduction campaigns.

CRM was developed by the laboratory of Yamaguchi is integrated in one database each company on another system decentralized information systems. Here, provides accurate customer information gathering, analysis and sharing. In addition, employees are working, you can take advantage of the system are. Plays the role of generating added value as a result, information infrastructure.

From this company is important, rather than in a specific department or human resources to implement CRM, employees share information, leverage and produce value added customer in problem-solving, while proposals to. It is a new concept of companies that cannot deliver value, judging by the value proposed by the companies using customer.

There are many types of chemical compounds in our environment, and some of them have negative effects on our bodies. Cigarette smoking is a risk factor for various diseases such as atherosclerosis, hypertention, COPD, and cancer. However, there are no clear information which chemical compounds in the cigarette smoke have negative effects on our bodies and cause these diseases. I have previously identified unsaturated carbonyl compounds as stable cytotoxic factors in the gas phase of cigarette smoke. The unsaturated carbonyl compounds are also contained in the smoke from combustion of organic materials such as woods, oil, coal. Thus, the unsaturated carbonyl compounds are regarded as environmental pollutants. The purpose of my study is elucidation of the molecular mechanisms for cytotoxicity of environmental pollutants including unsaturated carbonyl compounds.

Reproductive disorders in cows are major health and financial problems on farm. Endometritis and ovarian dysfunction such as cystic ovarian disease, ovarian quiescence, and ovulation failure often occur concurrently in cows. We have demonstrated that lipopolysaccharides (LPS) produced by Gram-negative bacteria suppress the function of granulosa cells in follicles, leading to ovarian dysfunction in cows.
It is our firm belief that further investigation for this mechanism are needed to enhance reproductive performance and support veterinarians on farm.

Typical gallbladder diseases in dogs include biliary sludge, gallbladder mucocele, and cholelithiasis, but the pathophysiology remains unclear. I am investigating safer treatment methods by clarifying the detailed pathophysiology of canine gallbladder disease.
In addition, the progress of diagnostic imaging technology in veterinary medicine is remarkable, and I am also working on the application of these data to surgical anatomy (vascular anatomy, etc.), and using these, considering a more safer surgical methods.

I am working for research on the causes, diagnosis and treatment of dermatosis and ear diseases in companion animals (dogs, cats and exotic pet animals). Furthermore, I am focusing on research on the treatment of infestation by fleas, ticks and Demodex mites. With regard to preventive veterinary medicine, the survey on the prevalence of infectious diseases in dogs and cats and further pharmacoepidemiological studies on vaccines, prophylactics for dirofilariasis, and ectoparasiticides for dogs and cats.

I am researching standards for exercising state jurisdiction in Internet. I am also researching ways to protect students from natural disasters. In addition, I am conducting a legal analysis of informed consent in veterinary medicine.

I aim to understand and evaluate the physical and mental conditions of livestock animals from the viewpoints of physiology and behavior, and to construct a rearing environment in which livestock animals can maximize their potential. In particular, we are conducting research on the effects of temperature on livestock animals and examining ways to supply healthy, safe, and high-quality livestock products to people even under climate change caused by global warming.

Teaching learning strategies that allow students to learn inquiringly in cooperation with their peers are attracting attention, as a learning activity that fosters 21st century academic ability, such as comprehensive inquiry time and inquiry activities for each subject that are included in the Course of Study and implemented at each school. In addition, the GIGA School Concept requires the use of ICT in such learning activities.
I am conducting research on effective teaching and learning strategies based on practical examples of inquiry-based learning, which is an educational activity required in such an era. In particular, practical training is emphasized in the Department of Informatics, and the development of learning materials and the accumulation of teaching plans are awaited so that students can acquire “information theory”, “information ethics”, “programming thinking ability”, and “practical ability to utilize information” by learning independently using ICT. Takahashi Laboratory has developed such teaching materials, analyzed practical cases, and conducted research on methods to measure the qualities and abilities of students, which is the basis for verifying their effectiveness.

We are conducting research using coordination chemistry techniques to create novel substances with unprecedented functionalities based on metal complexes. A metal complex is a compound in which a metal ion (such as copper or iron) forms strong bonds with surrounding molecules, known as ligands.
In metal complexes, the metal ion and ligands bind together in specific arrangements or shapes, forming a stable structure as a unified compound. Through these interactions, metal complexes can exhibit new functional properties that were not observed in the individual metal ions.
Recently, we have been synthesizing porphyrin derivatives containing metal ions at their centers and using these complexes as catalysts to explore oxidation reactions using only oxygen molecules from the air and light.

We aim to contribute to the development of the wine industries and education, through our research.
Research and invstigation into wine, Japanese sake, fruits and functional foods. Invesigation of volatile compaounds in wine and its produvtion mechanisms. Especially, advanced analysis and evaluation of wine.Wine has favorable and characteristic flavor. We indentify the characteristic compounds in wine and investigate their production mechanisms.
Wine have multiple health functionalities since it is a fermented material. We investigate the health functionality of wine and fermented foods in vitro.And, we investigate the health functinalities of functinal components fermented foods.

Most of the reserch on grape is about table grapes in Japan. Because wine grapes are not cultivated so much before. However, recently many wine grapes have been cultivated, and high quality wines are produced in several wineries in Japan. Until now engineers in wine makers have studies in the wine developped countries such as France and brought back the wine making techniques to Japan. But, Japanese climate and soil type are quite different from those of foreign countries. Then it is required to the Japanese original techniques in viticulture and enology. It is the most important thing in wine making that wine grapes are cultivated by the suitable conditions in Japan. Our institute of viticulture and enology aims to be a base for technology and information for engineers in wineries of the surrounding ares.

While using mechanical engineering (fluid dynamics, thermal engineering), applied physics (magneto science), and econometrics, I am conducting research on material informatics that integrates engineering and informatics. Practically, I analyze medical data using the methods of data mining and multivariate analysis. In the field of magneto science, I progress a technology called a “magnetic force booster” and succeeded in realizing a completely containerless protein crystal growth (see the photos). By the use of a magnetic levitation technique, I have also established in measuring the thermal properties of protein crystals.