When injection substances such as anesthetics to experimental animals, they should be pharmaceutical or veterinary grade or the Japanese Pharmacopoeia products, and scientific justification is required for the use of non-pharmaceutical grade compounds. Pentobarbital sodium has been used as an anesthetic for small laboratory rodents because of its rapid on set of effect, rapid loss of consciousness, and low cost compared to other anesthetics. However, this anesthetic is no longer marketed, and it has become necessary to find an alternative anesthetic to pentobarbital sodium. In this study, we will devise new anesthetic methods by combining anesthetics, sedatives, and analgesics that are currently manufactured and marketed as drugs.

I aim to understand and evaluate the physical and mental conditions of livestock animals from the viewpoints of physiology and behavior, and to construct a rearing environment in which livestock animals can maximize their potential. In particular, we are conducting research on the effects of temperature on livestock animals and examining ways to supply healthy, safe, and high-quality livestock products to people even under climate change caused by global warming.

We are concerned with biomimetic microstructure formed by self-spreading behavior of phospholipid molecular assembly in nanotechnology fields. Especially, a pollen like structure formed by egg-yolk phosphatidylcholine myelin figures has been studied by use of an optical microscopy. Budding of giant liposomes (GUV ~ 50µm) from the tip of spore like structure were observed. The size of GUV and the forming behavior were discussed using a geometric packing shape and a phase separation phenomenon of phospholipid molecules.

The difficult past was a catastrophic event that led to “mass death,” and the damage was felt not only by the dead but also by the survivors. This applies to wars, pollution damage, isolation policies for Hansen’s disease, pollution damage, etc. Furthermore, because such damage involves a complex relationship between perpetrators and victims, the “interpretation = meaning” of the event is likely to be divided depending on one’s position, making it difficult to pass on experiences. Based on the concepts of collaboration and ESD, I create spaces for dialogue, practice public history, and deepen my research on the inheritance of difficult past experiences.

The establishment of physique (body type) and physical fitness assessment methods that consider individual growth and development is an important issue in school health. In particular, for late adolescents (high school students), who are in the final stages of their physical growth, it is important from the perspective of future health to acquire physical fitness appropriate to their physique. However, conventional physical fitness assessment often overestimates (or underestimates) physical fitness. Hence, it is necessary to develop a new evaluation method that takes individual physique into account and can be practically implemented in educational settings. In our research, we have proposed a new physique assessment (body composition category model) based on the combination of fat mass and lean body mass. In the future, we will examine the validity of this model and the evaluation of physical fitness and athletic ability by body size, verify the validity of the evaluation table, and consider applying it to the educational field.

We are researching the nature of science education, such as student-led lesson development and creative questioning, to nurture children who love science and teachers who can truly enjoy science classes.

The vehicle speed is calculated from the rotation of the wheels, so errors occur due to tire wear and other factors. Methods using GPS and map information also have the problem of being easily affected by the environment and changes over time. Therefore, we focused on the patterns on the road patterns and developed a position estimation method by matching feature points on road surface images, and applied it to measuring the vehicle speed.
The speed estimation procedure is as follows : ① Deriving pairs of feature points on images with the same features. ② Findng geometry parameters by feature points, . ④ Calculating distance by majority pairs. An example of
speed calculation is shown in the
right figure. The relative error
with GPS is -5%.

We have developed a novel surface coating material called CAT that could induce cell self-assembling （Japanese patent No. 5746240, No. 6704197）. The single cell aggregate was formed by self-assembly of all cells adhered on CAT coated area. This technology enabled us to obtain 3D cell constructs having desired shapes and sizes automatically by only seeding cells on CAT printed culture dishes, which have great application potential for regenerative medicine, artificial organs and drug discovery as 3D tissue preparation tools.

We aim to contribute to the development of the wine industries and education, through our research.
Research and invstigation into wine, Japanese sake, fruits and functional foods. Invesigation of volatile compaounds in wine and its produvtion mechanisms. Especially, advanced analysis and evaluation of wine.Wine has favorable and characteristic flavor. We indentify the characteristic compounds in wine and investigate their production mechanisms.
Wine have multiple health functionalities since it is a fermented material. We investigate the health functionality of wine and fermented foods in vitro.And, we investigate the health functinalities of functinal components fermented foods.

We not only analyze the health status of humans, animals, the environment, and food, but also develop new testing methods to evaluate them.
In recent years, we have been conducting joint research with local governments and companies to develop processing methods to reduce food loss and add value to food ingredients, to evaluate the pharmacokinetics of functional ingredients in foods, and to develop new testing methods for inflammation markers.

We are developing soft actuators and soft sensors with flexibility and safety in life support devices and human frendly robot that act directly on humans. In addition, we are developing a pipe inspection robot that has a flexible structure by itself using a pneumatic actuator that can run on its own in complicated pipe and can be used in a wet narrow space. Then, in order to reduce the weight and labor of the peripheral equipment for driving the robot, we have devised a control valve with excellent cost performance and a new propulsion mechanism of the robot, and are considering making the inspection robot compact. Furthermore, we are developing local structure control technology by using burnishing as research on processing technology.

While using mechanical engineering (fluid dynamics, thermal engineering), applied physics (magneto science), and econometrics, I am conducting research on material informatics that integrates engineering and informatics. Practically, I analyze medical data using the methods of data mining and multivariate analysis. In the field of magneto science, I progress a technology called a “magnetic force booster” and succeeded in realizing a completely containerless protein crystal growth (see the photos). By the use of a magnetic levitation technique, I have also established in measuring the thermal properties of protein crystals.